Rodrigo Vazquez-Lombardi

Company: Engimmune

Job title: Chief Scientific Officer

Seminars:

Protein Engineering with Machine Learning (ML) for Specificity-Guided Development of Soluble TCR Engagers 10:50 am

• Specificity-guided affinity maturation. High sensitivity functional screens identify problematic off-targets early on • Expansion of the physically screenable sequence space with ML models. Coupling highthroughput data generation with ML predicts affinity- and specificity-enhanced variants • Activity-guided selection of optimal molecular format. Functional screening of TCR format library identifies optimal TCR-immunoligand configurationsRead more

day: Conference Day Two

Protein Engineering with Machine Learning (ML) for Specificity-Guided Development of Soluble TCR Engagers 11:30 am

Specificity-guided affinity maturation. High sensitivity functional screens identify problematic off-targets early on Expansion of the physically screenable sequence space with ML models. Coupling high-throughput data generation with ML predicts affinity- and specificity-enhanced variants Activity-guided selection of optimal molecular format. Functional screening of TCR format library identifies optimal TCR-immunoligand configurationsRead more

day: DAY TWO TRACK 1 A