Peggy Sotiropoulou

Company: T-Knife Therapeutics

Job title: Chief Scientific Officer

Seminars:

Integrating a Co-Stimulatory CD8 Co-Receptor & a Tailored Switch Receptor to Boost Persistence and Anti-Tumor Activity 2:15 pm

• Identifying inhibitory factors in the tumor microenvironment by large-scale tumor screening and translating these into activating signals through switch receptors • Leveraging inhibitory switch receptors to boost engraftment during TCR-T cell trafficking • Equipping cells with a costimulatory CD8 co-receptor to overcome lack of co-stimulatory signaling in the tumorRead more

day: Day 2

Panel Discussion: Evaluating the Cell vs Bispecific Evolution to Elevate Their Respective Advantages 10:00 am

• Consolidating the clinical advances for both approaches while highlighting the next generation for each method • Comparing clinical efficacy and safety data to highlight benefits and challenges of each modality • Discussing how the impact of various targets and TCR enhancements may differ for each approach to determine priorities for future modification • Reflecting…Read more

day: Day 1