Peggy Sotiropoulou

Chief Scientific Officer T-knife Therapeutics

Seminars

Monday 18th May 2026
Leveraging Novel Engineering Strategies to Overcome Tumor Escape & Amplify Potency
1:30 pm

As solid tumors continue to present challenges such as heterogeneity, immune evasion, and poor durability, the field is increasingly turning to advanced engineering solutions to redefine therapeutic potential. This workshop will explore cutting-edge approaches, from multi-antigen targeting strategies to next-generation TCR formats designed to amplify potency, mitigate tumor escape, and deliver deeper more durable responses that improve both patient outcomes and commercial viability.

Join this workshop to: 

  •  Develop multi-target strategies that reduce tumor escape and expand therapeutic reach across diverse solid tumor indications
  • Explore the engineering of next-generation constructs that maximize potency while maintaining safety and an optimal patient experience
  • Establish best practices for monitoring cell persistence using advanced bioanalytical assays
  • Assess half-life profiles to overcome dosing challenges while minimizing patient burden
Tuesday 19th May 2026
C-Level Fireside Chat: Reflecting on Lessons from TCR Therapies to Drive Next-Generation Strategies
9:00 am
  • Identifying pivotal learnings that can sharpen development strategies and accelerate stronger clinical outcomes
  • Framing actionable insights that translate early proof-of-concept gains into durable, real-world clinical impact
  • Exploring critical knowledge gaps and defining high-value priorities that can shape the next-generation of TCR innovations
Peggy Sotiropoulou speaker photo