Targeting HLA/Peptides with Cell-Based Therapies: Target Discovery, Binder Generation & Benchmarking TCR-T Cells vs TCR Mimetic-Based CAR-T Cells
Time: 12:00 pm
day: DAY ONE TRACK 1 A
Details:
- Proteogenomic/Immunopeptidomic pipeline for HLA/peptide target discovery/validation
- Robust in vivo platforms for TCR and TCRm antibody discovery
- Benchmarking TCR-T vs TCR mimetic-based CAR-T: TCR and CAR-T cells demonstrate differential tumor control, reflecting co-stimulatory signaling requirements
