Targeting HLA/Peptides with Cell-Based Therapies: Target Discovery, Binder Generation & Benchmarking TCR-T Cells vs TCR Mimetic-Based CAR-T Cells
Time: 11:15 am
day: Conference Day One
Details:
• Proteogenomic/Immunopeptidomic pipeline for HLA/peptide target discovery/validation
• Robust in vivo platforms for TCR and TCRm antibody discovery
• Benchmarking TCR-T vs TCR mimetic-based CAR-T: TCR and CAR-T cells demonstrate differential tumor control, reflecting co-stimulatory signaling requirements