Multiplexed TCRs Addressing HLA Loss in Solid Tumors
Time: 5:00 pm
day: DAY ONE TRACK 4 B
Details:
- Developing multiplexed TCRs with the ability to adapt and recognize tumor-specific antigens, compensating for potential HLA loss in the dynamic landscape of solid tumors
- Discussing engineering strategies enabling multiplexed TCRs to discern and target cancer cells even in scenarios of HLA downregulation, optimizing therapeutic efficacy
- Unveiling the potential of multiplexed TCRs to enhance therapeutic resilience by overcoming challenges associated with HLA loss