Enhancing Therapeutic Impact: Integrating Co- Stimulatory Signaling in TCR-T Therapies
Time: 3:30 pm
day: DAY ONE TRACK 3 A
Details:
- Explore how combining TCR-T therapy with co-stimulatory signaling approaches enhances T-cell activation and persistence, and efficacy
- Discuss the strategic choices in integration of co-stimulatory signaling, such as in the molecular designs of TCR-based Chimeric Antigen Receptor (TCR-CAR), to fine-tune immune responses, preventing exhaustion and augmenting durable anti-tumor effects in TCR-T clinical strategies
- Highlight the potential impact on therapeutic outcomes of integrating co-stimulatory signaling in TCR-T therapy, referring to the molecular designs of current clinically approved CAR-T therapies
