Sarah Leonard
Vice President, Preclinical Development, TCR-Based Therapeutics T-Cypher Bio
Seminars
Monday 18th May 2026
Discovering the Next-Generation of TCR Targets to Expand Patient Reach & Improve Therapeutic Impact
9:30 am
Uncover how the field is moving beyond familiar targets like MAGE-A4 and PRAME to identify novel antigens that expand patient reach and improve clinical outcomes. This workshop dives into cutting-edge technologies, non-canonical targets, and next-generation engineering strategies that are redefining TCR therapy. Gain practical insights into building robust discovery pipelines, validating tumor specificity, and designing therapies that stand out in a competitive landscape.
Join this workshop to:
- Explore emerging target spaces including non-canonical antigens, alternative HLA molecules, and strategies to increase prevalence and density for broader patient access
- Find new ways to expedite the target validation process using a broad range of tools
- Apply computational tools to discover and validate targets faster and more accurately
- Design next-generation TCR formats to maximize efficacy and durability of response