Using a Novel TGF-beta Switch to Prevent Exhaustion of T-Cells in the Solid TME
Time: 12:45 pm
day: Day 2
Details:
• Introduction of a novel TGF-beta Switch Receptor: explaining how the novel switch modulates TGF-beta signaling to enhance T-cell functionality within the hostile solid tumor microenvironment (TME)
• Preventing T-cell exhaustion: demonstrating how this approach effectively prevents T-cell exhaustion, enabling repeated killing
• Implications for advanced Immunotherapies: discussing the integration of this technology into the toolbox of technologies of Captain T Cell to develop more effective treatments for solid tumors
