Showcasing a Cellular TCR Evolution Platform to Upcycle TCRs for Clinical Deployment
Time: 11:35 am
day: Day 1
Details:
• A novel platform to generate clinically actionable TCRs beyond the native TCR repertoire
• Utilizing synthetic biology to diversify TCR frameworks and functionally select variants in T-cell libraries
• Validating optimized TCR for allo-reactivity and cross-reactivity to demonstrate safety
