Creating Robust Screens to Predict Cross-Reactivity & Off-Target Effects in Patients
Time: 12:15 pm
day: Day 1
Details:
• Analyzing TCR motifs to search the proteome and predict for potential off-target effects
• Determining the degree of similarity between TCR molecules and off-targets to ensure specificity for target antigen
• Minimizing cross-reactivity to allow for higher dose levels to increase the therapeutic window
