Developing a Robust, Antigen-Agnostic In Silico Prediction Model to Select & Test Personalized TCRs (pTCRs) for Tumor-Reactivity
Time: 12:15 pm
day: Day 1
Details:
- Predicting tumor-reactive pTCRs via gene signature to enable target diversity and rapid TCR discovery
- Generating wet-lab TCR validation data in a high-throughput format to train prediction model
- Validating selected pTCRs using patient-derived tumor organoids to inform preclinical efficacy
