Garrett Rappazzo
![Garrett Rappazzo Garrett Rappazzo](https://tcr-therapies-summit.com/wp-content/uploads/sites/181/2024/03/Screenshot-2024-03-28-155200-e1711641438968-150x150.png)
Company: Adimab LLC
Job title: Scientist
Seminars:
Rapid engineering of soluble T cell receptors for enhanced affinity via a high-throughput yeast-based platform 9:20 am
• Soluble T cell receptor (TCR)-based CD3 bispecific therapeutics can co-opt T cell function to eradicate virally infected and cancerous cells via peptide-HLA (pHLA) recognition. • Native TCRs require extensive affinity maturation for efficacy in clinically validated CD3 bispecific formats, posing a significant barrier to the development of soluble TCR-based therapeutics. • Adimab has developed…Read more
day: Conference Day Two