Selective T‑Cell Programming for Combinatorial CAR‑T/TCR‑T Solid Tumor Therapy

  • Describing a combinatorial CAR‑T and TCR‑T strategy for solid tumors enabled by targeted viral engineering
  • Paramyxovirus‑based pseudotyping will allow selective programming of distinct T‑cell subsets to generate complementary CAR‑T and TCR‑T products
  • Improving tumor recognition and address antigen heterogeneity