Noah Pefaur

Noah Pefaur

Company: Abbvie

Job title: Principle Scientist


Optimization of Targeting Domains For Bispecific T-Cell Engager Molecules 1:00 pm

• Most bispecific T-cell Engaging molecule programs contain multiple opportunities for optimization • Stable, specific targeting domains are an absolute requirement for TCE bispecifics, due to the high potency of the platform • Here we examine some general techniques we have found helpful to improve the drug like properties of soluble scFv and scTCR based…Read more

day: Day Two

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