Break Out Audience Discussion: Exploring the Importance of Target Binding Affinity and Avidity for Determining TCR-T Function

Time: 10:30 am
day: Focus Day


  • Discussing how the binding strength between a TCR and ligand influences the downstream function of the cell
  • Addressing how high affinity TCRs can negatively impact the function of the cell
  • Predicting optimal TCR-T function by measuring cell avidity
  • Improving surface levels of expression of TCRs