Break Out Audience Discussion: Exploring the Importance of Target Binding Affinity and Avidity for Determining TCR-T Function
Time: 10:30 am
day: Focus Day
Details:
- Discussing how the binding strength between a TCR and ligand influences the downstream function of the cell
- Addressing how high affinity TCRs can negatively impact the function of the cell
- Predicting optimal TCR-T function by measuring cell avidity
- Improving surface levels of expression of TCRs
